The likely epidemiological sources of the
transmitted mumps virus were children who were recently vaccinated with the
mumps vaccine containing Leningrad-Zagreb or Leningrad-3 MuV. The etiology of
the described cases of the horizontal transmission of both mumps vaccine
viruses was confirmed by PCR with the sequential restriction analysis.
The likely epidemiological source of the
transmitted L-3 mumps virus was children who were recently vaccinated at the
schools attended by the six symptomatic mumps patients described here
Mumps outbreak in Netherlands linked to those
vaccinated twice with MMR:
We found 18 reports of measles outbreaks in
very highly immunized school populations where 71% to 99.8% of students were
immunized against measles. Despite these high rates of immunization, 30% to
100% (mean, 77%) of all measles cases in these outbreaks occurred in previously
immunized students. In our hypothetical school model, after more than 95% of
schoolchildren are immunized against measles, the majority of measles cases occur
in appropriately immunized children.
Measles virus RNA was detected as early as 1
day or as late as 14 days after vaccination. Measles virus RNA was also
detected in the urine samples from all four of the young adults between 1 and
13 days after vaccination. This assay will enable continued studies of the
shedding and transmission of measles virus and, it is hoped, will provide a
rapid means to identify measles infection, especially in mild or asymptomatic
cases.
Measles virus was isolated in a throat swab
taken 4 days after fever onset. This virus was then further genetically characterised as a
vaccine-type virus
http://www.sciencedirect.com/science/article/pii/S0264410X01004959
http://www.sciencedirect.com/science/article/pii/S0264410X01004959
An infant boy with a congenital
immunodeficiency had fatal disseminated measles after administration of a live
attenuated measles vaccine
BROTHER-TO-SISTER TRANSMISSION OF MEASLES
AFTER MEASLES, MUMPS, AND RUBELLA IMMUNISATION
We describe excretion of measles vaccine
strain Schwarz in a child who developed a febrile rash illness eight days after
primary immunisation against measles, mumps and rubella
We report a case of measles inclusion-body
encephalitis (MIBE) occurring in an apparently healthy 21-month-old boy 8.5
months after measles-mumps-rubella vaccination
SEVERAL acute systemic viral illnesses have
been associated with the presence of multinucleated giant cells or
inclusion-bearing cells (or both) detected in nasal discharges1 and specimens
of urine in human patients. Such cells have also been observed in the urinary
sediments of children vaccinated with poliovirus and measles
Small Pox vaccine sheds to toddler from parent
(military personnel)
http://mobile.nytimes.com/2007/05/18/health/18smallpox.html
http://mobile.nytimes.com/2007/05/18/health/18smallpox.html
A 12-month-old healthy boy had approximately
30 vesicular skin lesions 24 days after receiving varicella vaccine. Sixteen
days later his pregnant mother had 100 lesions. Varicella-vaccine virus was
identified by polymerase chain reaction in the vesicular lesions of the mother.
This case documents transmission of varicella-vaccine virus from a healthy
12-month-old infant to his pregnant mother.
Zostavax contains live attenuated VZV, and the
package insert warns newly vaccinated individuals to avoid contact for an
unspecified time with newborn infants, immunosuppressed individuals, and
pregnant women who have not had chicken pox or have not been immunized for
chicken pox. Because VZV DNA is present in saliva of zoster patients for at
least 2 weeks [5] and VZV in saliva can also be infectious [6], we examined the
inoculation site and saliva of Zostavax-vaccinated subjects for the presence of
VZV DNA for 4 weeks after immunization”
“Vaccine-type rotavirus was detected in all 50
antigen-positive specimens and 8 of 8 antigen-negative specimens. Nine (75%) of
12 EIA-positive and 1 EIA-negative samples tested culture-positive for
vaccine-type rotavirus. Fecal shedding of rotavirus vaccine virus after the
first dose of RV5 occurred over a wide range of post-vaccination days not
previously studied.”
“The RotaTeq vaccine contains five live,
attenuated strains derived through laboratory reassortment of human rotavirus
strains with a bovine rotavirus strain. Three RotaTeq strains each contain a single
human rotavirus gene segment and ten bovine rotavirus segments, and two strains
contain two human strain segments and nine bovine strain segments. In the
study, RotaTeq was detected in 16 stool samples. Ten of these contained between
one and four individual vaccine component strains. Six samples were found to
contain a vaccine-derived G1P[8] (vdG1P[8]) strain. vdG1P[8] is believed to be
the product of a genetic reassortment event in which the G1 gene segment of
strain WI79-9 is inserted into strain WI79-4, as evidenced by the association
of G1-VP7 and P[8]-VP4 human rotavirus genes with the M2-VP3 and I2-VP6 of the
bovine rotavirus. Donato et al. observed that approximately a fifth of the
infants having diarrhea within 2 weeks of rotavirus vaccination were shedding
vaccine strain components exclusive of any detectable enteric pathogen.”
Post-marketing experience suggests that
transmission of vaccine virus may occur rarely between healthy vaccinees who
develop a varicella-like rash and healthy susceptible contacts. Transmission of
vaccine virus from a mother who did not develop a varicella-like rash to her
newborn infant has been reported.
Due to the concern for transmission of vaccine virus, vaccine recipients should attempt to avoid whenever possible close association with susceptible high-risk individuals for up to six weeks following vaccination with VARIVAX
Due to the concern for transmission of vaccine virus, vaccine recipients should attempt to avoid whenever possible close association with susceptible high-risk individuals for up to six weeks following vaccination with VARIVAX
Rotavirus shedding in stool occursafter
vaccination with peak excretion occurring around Day7after Dose
https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Rotarix/pdf/ROTARIX-PI-PIL.PDF
Analysis of 36 individuals over age 60 years
who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in
swabs of skin inoculation sites obtained immediately after immunization.
vaccine virus DNA is shed in saliva up to 4 weeks
conclude that acellular vaccines may well have
contributed to -- even exacerbated -- the recent pertussis outbreak by allowing
infected individuals without symptoms to unknowingly spread pertussis multiple
times in their lifetimes
Investigation of a measles outbreak in a fully
vaccinated school population including serum studies before and after
revaccination
http://www.ncbi.nlm.nih.gov/pubmed/8483623
http://www.ncbi.nlm.nih.gov/pubmed/8483623
According to statistics, the majority of
outbreaks occur in populations where the majority of individuals were
previously vaccinated.
http://aje.oxfordjournals.org/content/139/1/77.short
http://aje.oxfordjournals.org/content/139/1/77.short
Correction: This article and an accompanying
video previously included a photograph of a child with a rash linked to a
vaccination. The image has been removed.
Clark County Public Health said 3 people
suspected of having measles earlier this week had rashes, but those rashes were
simply reactions to the MMR vaccine and not the measles virus.
Examples:
CORRECTION: An earlier version of this
story showed a file photograph of a child who had an adverse reaction to the
MMR vaccine. Due to an editing error, the child was misidentified in the
caption as having measles. CBSDFW apologizes for the error.
Seattle Children's Hospital says the patient
was one of its nurses who was working with a child who had contracted measles.
They say she was fully vaccinated and was wearing protective equipment but
still contracted the disease anyway.
Officials said specialized laboratory testing
was done after it was learned that the child had been vaccinated days before
being diagnosed with measles. The tests determined that the child was
experiencing symptoms of a vaccine reaction, rather than measles.
The child is vaccinated, did not have any
serious complications, and is fully recovered from the disease
The child is vaccinated, did not have any
serious complications, and is fully recovered from the disease
University of Florida spokesperson Steve
Orlando confirmed there are 24 cases of the mumps on campus. All 24 students were
vaccinated.
McCabe said she was vaccinated twice and
tested positive for presumed immunity against measles three times in the last
20 years
The person was fully immunized but came into
contact with an 11-month-old San Diego resident who contracted the disease
after a recent trip to the Philippines.
The Student Health Center says all of the
students had received required doses of the vaccine to prevent mumps.
Even those who have been fully vaccinated can
still catch the disease, and so far all of the children who have caught the
virus were vaccinated, Smith said
All students effected up to date.
The public health department in Cambridge,
Mass., where Harvard is located, determined a month ago that all infected
students to that point had received a mumps vaccine prior to contracting the
infection
Some 97% of those in the Ohio outbreak have
been vaccinated
https://www.cnn.com/2014/03/24/health/ohio-mumps
The Navy's Bureau of Medicine and Surgery
(BUMED) later explained to BI that "based on clinical presentation and
laboratory testing, these cases are currently classified as probable cases of
mumps," one of a number of illnesses that all US military personnel are
vaccinated against
A whooping cough outbreak is causing
concern in Summit County as 19 children have been diagnosed, and it's the first
time in years Park City schools have seen a case of pertussis.
Officials said all of the children who have
been diagnosed were vaccinated against the illness.
https://fox13now.com/2015/03/27/19-kids-in-summit-co-diagnosed-with-whooping-cough-despite-being-up-to-date-on-vaccinations/
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